Kunz E, Mätz-Rensing K, Stolte N, Hamilton P B, Kaup F J
Department of Primate Veterinary Medicine and Primate Husbandry, German Primate Center, 37077 Göttingen, Germany.
Vet Pathol. 2002 Nov;39(6):721-5. doi: 10.1354/vp.39-6-721.
Trypanosoma cruzi-like flagellates were incidentally noted in blood smears of a routinely monitored rhesus monkey experimentally infected with the simian immunodeficiency virus (SIV). Immunodeficiency in the course of the SIV infection reactivated a chronic infection of Chagas' disease that had been unnoticed when the macaque was imported to Europe. The animal developed no specific clinical symptoms of American trypanosomiasis, but histologically a chagasic myocarditis was detected. Analysis of the small subunit rRNA gene of the trypanosome identified the protozoan as T. cruzi.
在一只经实验感染猿猴免疫缺陷病毒（SIV）的恒河猴的血液涂片检查中，偶然发现了类似克氏锥虫的鞭毛虫。SIV感染过程中的免疫缺陷激活了恰加斯病的慢性感染，这一感染在猕猴被引入欧洲时未被察觉。这只动物未出现美洲锥虫病的特定临床症状，但在组织学上检测到了恰加斯性心肌炎。对锥虫的小亚基rRNA基因分析确定该原生动物为克氏锥虫。
