Capoglu I, Yilmaz A B, Unüvar N, Orbak R, Aksoy H, Yesilyurt H
Atatürk University Medical Faculty, Department of Endocrinology, Erzurum, Turkey.
Endocrine. 2002 Aug;18(3):207-10. doi: 10.1385/ENDO:18:3:207.
In this study, we investigated gingival enlargement in patients with acromegaly as a component of the disease. Eleven patients (5 males, 6 females) were evaluated. Diagnosis was confirmed with typical clinical features and laboratory. Oral examinations were carried out by the same periodontist. During the examination, plaque index, gingival index, probing pocket depths, and gingival enlargement values were evaluated. Duration of the disease was between 0.2 and 13 yr. Seven patients had pituitary macroadenomas and four had microadenomas during their initial diagnosis. Only one patient was newly diagnosed. The other patients had previously undergone surgery. Gingival enlargement was found in eight patients. Seven patients with gingival enlargement also had prognathism, and one patient had prognathism associated with gingival enlargement. These findings demonstrate that acromegaly that results in overgrowth in various organs should be considered one of the causes of gingival enlargement.
在本研究中，我们将肢端肥大症患者的牙龈增生作为该疾病的一个组成部分进行了调查。对11例患者（5例男性，6例女性）进行了评估。通过典型的临床特征和实验室检查确诊。口腔检查由同一位牙周病医生进行。检查期间，评估了菌斑指数、牙龈指数、探诊深度和牙龈增生值。病程在0.2至13年之间。7例患者在初次诊断时患有垂体大腺瘤，4例患有微腺瘤。只有1例患者是新诊断出的。其他患者此前已接受过手术。8例患者发现有牙龈增生。7例牙龈增生患者也有下颌前突，1例患者的下颌前突与牙龈增生有关。这些发现表明，导致各器官过度生长的肢端肥大症应被视为牙龈增生的原因之一。
