（2-羟基丁基）-正丁基亚硝胺的大鼠尿液代谢产物
[Rat urinary metabolites of (2-hydroxybutyl)-n-butylnitrosamine].
作者信息
Blattmann L, Preussmann R
出版信息
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1975;83(2):125-7. doi: 10.1007/BF00282979.
PMID:124517
Abstract
The chemical structure of 3 urinary metabolites of 2-hydroxy-di-n-butylnitrosamine has been identified by mass spectrometry. The results indicate that oxidation and formation of metabolites with shorter chain length may be explained by alpha-oxidation and subsequent degradation. This is an alternative to the beta-oxidation hypothesis of Krüger (1971).
摘要
通过质谱分析法已鉴定出2-羟基-二正丁基亚硝胺的3种尿液代谢物的化学结构。结果表明，具有较短链长度的代谢物的氧化和形成可能可用α-氧化及随后的降解来解释。这是对Krüger（1971年）的β-氧化假说的一种替代。
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