国家结核病基因分型与监测网络的基本原理和方法
Rationale and methods for the National Tuberculosis Genotyping and Surveillance Network.
作者信息
Castro Kenneth G, Jaffe Harold W
机构信息
Division of Tuberculosis Elimination, National Center for HIV, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
出版信息
Emerg Infect Dis. 2002 Nov;8(11):1188-91. doi: 10.3201/eid0811.020408.
Abstract
Our understanding of tuberculosis (TB) transmission dynamics has been refined by genotyping of Mycobacterium tuberculosis strains. The National Tuberculosis Genotyping and Surveillance Network was designed and implemented to systematically evaluate the role of genotyping technology in improving TB prevention and control activities. Genotyping proved a useful adjunct to investigations of outbreaks, unusual clusters, and laboratory cross-contamination.
摘要
我们对结核病（TB）传播动态的理解已通过结核分枝杆菌菌株的基因分型得到完善。国家结核病基因分型与监测网络的设计与实施，旨在系统评估基因分型技术在改善结核病预防与控制活动中的作用。基因分型被证明是疫情调查、异常聚集以及实验室交叉污染调查的有用辅助手段。
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