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2
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HIV-1 and recurrence, relapse, and reinfection of tuberculosis after cure: a cohort study in South African mineworkers.HIV-1与结核病治愈后的复发、再发及再感染:一项针对南非矿工的队列研究
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Transmission of multidrug-resistant Mycobacterium tuberculosis among persons with human immunodeficiency virus infection in an urban hospital: epidemiologic and restriction fragment length polymorphism analysis.城市医院中人类免疫缺陷病毒感染者之间耐多药结核分枝杆菌的传播:流行病学及限制性片段长度多态性分析
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国家结核病基因分型与监测网络的基本原理和方法

Rationale and methods for the National Tuberculosis Genotyping and Surveillance Network.

作者信息

Castro Kenneth G, Jaffe Harold W

机构信息

Division of Tuberculosis Elimination, National Center for HIV, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

出版信息

Emerg Infect Dis. 2002 Nov;8(11):1188-91. doi: 10.3201/eid0811.020408.

DOI:10.3201/eid0811.020408
PMID:12453341
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2738540/
Abstract

Our understanding of tuberculosis (TB) transmission dynamics has been refined by genotyping of Mycobacterium tuberculosis strains. The National Tuberculosis Genotyping and Surveillance Network was designed and implemented to systematically evaluate the role of genotyping technology in improving TB prevention and control activities. Genotyping proved a useful adjunct to investigations of outbreaks, unusual clusters, and laboratory cross-contamination.

摘要

我们对结核病(TB)传播动态的理解已通过结核分枝杆菌菌株的基因分型得到完善。国家结核病基因分型与监测网络的设计与实施,旨在系统评估基因分型技术在改善结核病预防与控制活动中的作用。基因分型被证明是疫情调查、异常聚集以及实验室交叉污染调查的有用辅助手段。