Sanders David Avram
Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.
Curr Opin Biotechnol. 2002 Oct;13(5):437-42. doi: 10.1016/s0958-1669(02)00374-9.
Pseudotyped vectors can be used to introduce genes into cells or to study the entry process of the virus from which the outer shell of the recombinant virus is derived. Recently, several novel pseudotyped retroviruses and lentiviruses have been constructed. Virus vectors pseudotyped with an alphavirus glycoprotein hold special promise. The increasing diversity of the available pseudotyped vectors offers expanded opportunities for gene transfer to specific cells.
假型载体可用于将基因导入细胞，或研究重组病毒外壳所源自的病毒的进入过程。最近，已经构建了几种新型的假型逆转录病毒和慢病毒。用甲病毒糖蛋白假型化的病毒载体具有特殊的前景。可用假型载体的日益多样化为将基因转移到特定细胞提供了更多机会。
