Bosin T R, Campaigne E, Dinner A, Rogers R B, Maickel R P
J Toxicol Environ Health. 1976 Jan;1(3):515-20. doi: 10.1080/15287397609529350.
The comparative LD50 values have been determined in mice for 34 indole, benzo[b] thiophene, and 1-methylindole derivatives of related structures. No clear-cut correlations could be obtained with regard to physicochemical properties across all structures although some relationships are evident within subgroups.
已测定了34种具有相关结构的吲哚、苯并[b]噻吩和1-甲基吲哚衍生物在小鼠体内的半数致死剂量(LD50)比较值。尽管在亚组内有一些明显的关系,但就所有结构的物理化学性质而言,未能获得明确的相关性。