从日本扁柏（柏科）中分离并鉴定花旗松素3 - O - 葡萄糖苷异构体

Separation and identification of Taxifolin 3-O-glucoside isomers from Chamaecyparis obtusa (Cupressaceae).

作者信息

Sakushima Akiyo, Ohno Kosei, Coskun Makusut, Seki Koh-Ichi, Ohkura Kazue

机构信息

Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0212, Japan.

出版信息

Nat Prod Lett. 2002 Dec;16(6):383-7. doi: 10.1080/10575630290033141.

DOI:10.1080/10575630290033141

PMID:12462342

Abstract

Taxifolin 3-O-glucoside isomers, [(2R, 3R)-, (2R, 3S)-, (2S, 3R)- and (2S, 3S)-] were isolated from leaves of Chamaecyparis obtuse (Cupressaceae). Their structures were elucidated on the basis of UV, MS, CD, 1H- and 13C-NMR spectral data, including 2D shift correlation. It was found that the compounds could be distinguished by the use of 1H- and 13C-NMR spectral data.

摘要

从钝叶扁柏（柏科）的叶子中分离出了taxifolin 3-O-葡萄糖苷异构体，即[(2R, 3R)-、(2R, 3S)-、(2S, 3R)-和(2S, 3S)-]。基于紫外光谱、质谱、圆二色光谱、1H-和13C-核磁共振光谱数据（包括二维位移相关）阐明了它们的结构。结果发现，这些化合物可以通过1H-和13C-核磁共振光谱数据来区分。