Department of Pharmacognosy and Herbal Medicines, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wroclaw, Poland.
Molecules. 2022 Aug 19;27(16):5293. doi: 10.3390/molecules27165293.
Strawberry leaves are considered a valuable waste material; so far, mainly due to their antioxidant properties. Since the annual production of this crop is high, our study aimed to thoroughly examine the chemical composition and antidiabetes-related bioactivity of × leaf of its popular and productive cultivar Senga Sengana. Leaves from three different seasons, collected after fruiting, were extensively analyzed (UHPLC-qTOF-MS/MS, HPLC-DAD). Some individual components were isolated and quantified, including specific flavonol diglycosides (e.g., 3--[β-xylosyl(1‴→2″)]-β-glucuronosides). The separated quercetin glycosides were tested in an antiglycation assay, and their methylglyoxal uptake capacity was measured. In addition, the biodegradable polyester precursor 2-pyrone-4,6-dicarboxylic acid (PDC) was confirmed at relatively high levels, providing further opportunity for strawberry leaf utilization. We want to bring to the attention of the food, pharmaceutical, and cosmetic industries the Senga Sengana strawberry leaf as a new botanical raw material. It is rich in PDC, ellagitannins, and flavonols-potent glycation inhibitors.
草莓叶被认为是一种有价值的废物材料；到目前为止，主要是由于其抗氧化特性。由于这种作物的年生产量很高，我们的研究旨在彻底研究其广受欢迎和高产品种 Senga Sengana 的 × 叶的化学成分和抗糖尿病相关的生物活性。在果实收获后，从三个不同季节采集的叶子进行了广泛分析（UHPLC-qTOF-MS/MS、HPLC-DAD）。分离并定量了一些单体成分，包括特定的黄酮醇二糖苷（例如，3--[β-木糖基（1‴→2″）]-β-葡萄糖醛酸苷）。分离出的槲皮素糖苷在糖基化抑制试验中进行了测试，并测量了它们对甲基乙二醛的摄取能力。此外，还证实了相对较高水平的可生物降解聚酯前体 2-吡喃酮-4,6-二羧酸（PDC），为草莓叶的利用提供了更多机会。我们希望引起食品、制药和化妆品行业的关注，将 Senga Sengana 草莓叶作为一种新的植物原料。它富含 PDC、鞣花单宁和类黄酮——强效糖基化抑制剂。
