Smailes S T
St. Andrew's Centre for Plastic Surgery and Burns, Broomfield Hospital, Broomfield, CM1 7ET, Chelmsford, UK
Burns. 2002 Dec;28(8):795-801. doi: 10.1016/s0305-4179(02)00197-3.
Acute respiratory failure is a common complication of the severely burn-injured patient. Endotracheal intubation and mechanical ventilation is associated with a high rate of complications. Noninvasive Positive Pressure Ventilation (NIPPV) has been shown to be as effective as conventional ventilation in improving gas exchange and is associated with fewer complications with patients in acute hypercapnic and hypoxaemic respiratory failure. We report our experience with NIPPV in 30 burn patients.
The records of all burn patients from 1998 to 2000, where NIPPV was used as part of their management at the St. Andrew's Centre for Plastic Surgery and Burns, were reviewed.
Mean age was 47.56 years (range 12-81). Nine patients were female. Mean burn size was 24.4% total body surface area (TBSA) (range 3-54). Inhalation injury was confirmed in eight cases. A positive diagnosis of pneumonia was made in 29 patients. The mean PaO(2)/FiO(2) ratio prior to institution of NIPPV was 28.98Kpa (range 8.75-52). Intermittent Positive Pressure Breathing (IPPB) was the most common ventilatory mode employed (25 patients) and the face mask was the most used interface (18 cases). Twenty-two patients (74%) avoided endotracheal intubation and their respiratory function continued to improve after NIPPV was discontinued. One patient (3%) died and seven patients (23%) were reintubated. Three out of the seven were electively reintubated for burns surgery.
In burn-injured patients with acute respiratory failure, NIPPV appears to be effective in supporting respiratory function such that endotracheal intubation can be avoided in most cases.
急性呼吸衰竭是重度烧伤患者的常见并发症。气管插管和机械通气会带来较高的并发症发生率。无创正压通气(NIPPV)已被证明在改善气体交换方面与传统通气同样有效,且在急性高碳酸血症和低氧血症呼吸衰竭患者中并发症较少。我们报告30例烧伤患者使用NIPPV的经验。
回顾了1998年至2000年在圣安德鲁整形外科与烧伤中心接受治疗的所有使用NIPPV作为治疗一部分的烧伤患者的记录。
平均年龄为47.56岁(范围12 - 81岁)。9例为女性。平均烧伤面积为全身表面积(TBSA)的24.4%(范围3% - 54%)。8例确诊有吸入性损伤。29例患者确诊为肺炎。开始使用NIPPV前的平均PaO₂/FiO₂比值为28.98Kpa(范围8.75 - 52)。间歇正压通气(IPPB)是最常用的通气模式(25例患者),面罩是最常用的接口(18例)。22例患者(74%)避免了气管插管,停用NIPPV后其呼吸功能持续改善。1例患者(3%)死亡,7例患者(23%)再次插管。7例中有3例因烧伤手术而择期再次插管。
在急性呼吸衰竭的烧伤患者中,NIPPV似乎能有效支持呼吸功能,使得大多数情况下可避免气管插管。