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外周动脉栓塞患者临床趋势的变化

Changing clinical trends in patients with peripheral arterial emboli.

作者信息

Hight D W, Tilney N, Couch N P

出版信息

Surgery. 1976 Feb;79(02):172-6.

PMID:1246675
Abstract

One hundred and twenty-four patients treated by Fogarty balloon catheter embolectomy from 1964 through 1973 were reviewed and compared to an earlier series of 82 patients treated by direct extraction during the interval from 1948 to 1963. In patients undergoing embolectomy, the incidence of rheumatic heart disease (RHD) declined from 55 to 27 percent, and that of arteriosclerotic heart disease (ASHD) rose from 39 to 55 percent. The operative mortality rate of those with RHD was unchanged and that of patients with ASHD declined from 74 to 36 percent. This was attributed, in part, to the lesser degree of operative stress entailed by the Fogarty catheter and the local anesthesia. Limb salvage was 82 percent when ischemic symptoms were less than 24 hours in duration and 66 percent when such symptoms were more than 24 hours in duration. The amputation rate for the entire group was 22 percent. The low 2 year survival of patients with ASHD and of amputees was ascribed to the wide extent of their atherosclerotic cardiovascular disease. This was emphasized by the fact that 44 percent of late deaths were due to myocardial infarction.

摘要

回顾了1964年至1973年期间接受Fogarty球囊导管取栓术治疗的124例患者,并与1948年至1963年期间接受直接取栓治疗的早期82例患者系列进行了比较。在接受取栓术的患者中,风湿性心脏病(RHD)的发病率从55%降至27%,而动脉硬化性心脏病(ASHD)的发病率从39%升至55%。RHD患者的手术死亡率没有变化,而ASHD患者的手术死亡率从74%降至36%。这部分归因于Fogarty导管带来的手术应激程度较低以及局部麻醉。当缺血症状持续时间少于24小时时,肢体挽救率为82%;当症状持续时间超过24小时时,肢体挽救率为66%。整个组的截肢率为22%。ASHD患者和截肢者较低的2年生存率归因于其广泛的动脉粥样硬化性心血管疾病。44%的晚期死亡归因于心肌梗死这一事实强调了这一点。

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