Ruano-Ravina Alberto, Figueiras Adolfo, Dosil-Diaz Olga, Barreiro-Carracedo Ana, Barros-Dios Juan Miguel
Department of Preventive Medicine and Public Health, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain.
Nutr Cancer. 2002;43(1):47-51. doi: 10.1207/S15327914NC431_5.
A population-based case-control study was carried out in Northwest Spain to analyze the effect of fruit and vegetable intake on the appearance of lung cancer. A non-significant protective association was found for overall consumption of leafy green and other vegetables, with consumption once a day or more vs. less than once a week yielding odds ratios of 0.63 [95% confidence interval (CI) = 0.24-1.63] for leafy green vegetables and 0.64 (95% CI = 0.30-1.36) for other vegetables. A significant protective association was found for potato consumption. No protective associations were recorded for fruit, whether overall or singly; instead, fruit consumption once a day or more vs. less than once a week registered a risk of 2.16 (95% CI = 1.02-4.58). Although the possibility that this effect may be due to a phenomenon of reverse causation cannot be ruled out, these results could support other reports and hypotheses which indicate that the protective effect of fruit might not be as pronounced as generally thought.
在西班牙西北部开展了一项基于人群的病例对照研究，以分析水果和蔬菜摄入量对肺癌发病的影响。对于绿叶蔬菜和其他蔬菜的总体摄入量，发现了一种无统计学意义的保护关联，每天食用一次或更多次与每周少于一次相比，绿叶蔬菜的比值比为0.63 [95%置信区间(CI)=0.24 - 1.63]，其他蔬菜的比值比为0.64(95% CI = 0.30 - 1.36)。发现土豆摄入量存在显著的保护关联。对于水果，无论是总体摄入还是单一摄入，均未记录到保护关联；相反，每天食用一次或更多次与每周少于一次相比，水果摄入的风险为2.16(95% CI = 1.02 - 4.58)。尽管不能排除这种效应可能是由于反向因果关系现象所致的可能性，但这些结果可能支持其他报告和假设，即水果的保护作用可能不像普遍认为的那样显著。
