曼哈顿北部中风研究中的青年中风情况

Stroke in the young in the northern Manhattan stroke study.

作者信息

Jacobs Bradley S, Boden-Albala Bernadette, Lin I-Feng, Sacco Ralph L

机构信息

Wayne State University/Detroit Medical Center Comprehensive Stroke Program, Department of Neurology, Wayne State University School of Medicine, Detroit, Michigan, USA.

出版信息

Stroke. 2002 Dec;33(12):2789-93. doi: 10.1161/01.str.0000038988.64376.3a.

DOI:10.1161/01.str.0000038988.64376.3a

PMID:12468771

Abstract

BACKGROUND AND PURPOSE

Stroke and stroke subtype incidence in young black and Hispanic populations have not been well studied. The purpose of this study was to determine stroke incidence rates in these populations and to compare rates among various race-ethnic, sex, and age groups.

METHODS

A population-based incidence study identified all cases of first stroke in Northern Manhattan from 1993 to 1997. Stroke and stroke subtype incidence rates were calculated for younger (20 to 44 years of age) and older (>/=45 years of age) adults. The relative risk (RR) of stroke in blacks and Hispanics compared with whites was calculated. Stroke subtypes, infarct subtypes, and case fatality rates were compared in the young and old and in different race-ethnic groups and sexes.

RESULTS

Over 4 years, 74 cases of first stroke in young patients were discovered (47% women, 12% black, 80% Hispanic, 8% white). The stroke incidence rates (cases per 100 000 persons per year) in the young were 23 overall, 10 for infarct, 7 for intracerebral hemorrhage (ICH), and 6 for subarachnoid hemorrhage. The RR of stroke in the young was greatest for blacks (2.4; 95% CI, 0.8 to 6.7) and Hispanics (2.5; 95% CI, 1.1 to 5.8) compared with whites. ICH was more frequent in men with a RR of 3.7 (95% CI, 1.4 to 10.1). Case fatality rates at 30 days were higher in blacks (38%) and Hispanics (16%) compared with whites (0%).

CONCLUSIONS

Young blacks and Hispanics have greater stroke incidences than young whites.

摘要

背景与目的

年轻黑人和西班牙裔人群中中风及中风亚型的发病率尚未得到充分研究。本研究的目的是确定这些人群中的中风发病率，并比较不同种族、性别和年龄组之间的发病率。

方法

一项基于人群的发病率研究确定了1993年至1997年在曼哈顿北部首次发生中风的所有病例。计算了年轻（20至44岁）和年长（≥45岁）成年人的中风及中风亚型发病率。计算了黑人和西班牙裔与白人相比中风的相对风险（RR）。比较了年轻人和老年人以及不同种族、性别组中的中风亚型、梗死亚型和病死率。

结果

在4年期间，发现了74例年轻患者首次中风病例（女性占47%，黑人占12%，西班牙裔占80%，白人占8%）。年轻人的中风发病率（每年每10万人中的病例数）总体为23，梗死为10，脑出血（ICH）为7，蛛网膜下腔出血为6。与白人相比，年轻人中中风RR最高的是黑人（2.4；95%CI，0.8至6.7）和西班牙裔（2.5；95%CI，1.1至5.8）。ICH在男性中更常见，RR为3.7（95%CI，1.4至10.1）。与白人（0%）相比，黑人（38%）和西班牙裔（16%）的30天病死率更高。