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美国母乳监测与环境化学物质研究技术研讨会概述

Technical workshop on human milk surveillance and research on environmental chemicals in the United States: an overview.

作者信息

LaKind Judy S, Berlin Cheston M

机构信息

LaKind Associates, LLC, Catonsville, Maryland, USA.

出版信息

J Toxicol Environ Health A. 2002 Nov 22;65(22):1829-37. doi: 10.1080/00984100290071739.

Abstract

Interest in human milk research and monitoring for environmental chemicals is growing, and as studies of chemicals in human milk are initiated, it is of the utmost importance that these studies be conducted using harmonized methods. Due to numerous limitations in previous studies and the fact that few studies on environmental chemicals in human milk have been conducted in the United States, there is a growing need for a human milk sampling and analysis protocol in this country. The Technical Workshop on Human Milk Surveillance and Research on Environmental Chemicals in the United States was organized to develop state-of-the-science protocols describing the various aspects of such a program. An expert panel, comprised of specialists in the fields of pediatrics, family medicine, nursing, lactation, human milk sampling, analytical chemistry, epidemiology, pharmacology, toxicology, nutrition, and risk evaluation and communication, was assembled to participate in a 2-day workshop at the Milton S. Hershey Medical Center, Pennsylvania State University College of Medicine. The expert panel was tasked with carefully describing and defining the components of well-conducted human milk surveillance and research studies, including participant selection, sample collection and analysis techniques, questionnaire development, chemical selection, and data reporting and interpretation, especially for use in the United States. The articles that follow this overview describe the results of the expert panel's deliberations on the components of human milk surveillance and research programs.

摘要

对人乳研究以及监测其中环境化学物质的兴趣日益浓厚。随着针对人乳中化学物质的研究陆续开展,采用统一的方法进行这些研究至关重要。鉴于以往研究存在诸多局限性,且美国国内针对人乳中环境化学物质的研究较少,该国对人乳采样与分析方案的需求日益增长。美国组织了人乳环境化学物质监测与研究技术研讨会,旨在制定描述此类项目各个方面的科学方案。一个专家小组汇聚一堂,成员包括儿科学、家庭医学、护理学、泌乳学、人乳采样、分析化学、流行病学、药理学、毒理学、营养学以及风险评估与沟通等领域的专家,他们在宾夕法尼亚州立大学医学院米尔顿·S·赫尔希医疗中心参加了为期两天的研讨会。专家小组的任务是仔细描述和界定开展良好的人乳监测与研究的组成部分,包括参与者选择、样本采集与分析技术、问卷编制、化学物质选择以及数据报告与解读,特别是适用于美国的情况。本综述之后的文章描述了专家小组就人乳监测与研究项目组成部分进行审议的结果。

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