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青春期的生长

Growth at puberty.

作者信息

Rogol Alan D, Roemmich James N, Clark Pamela A

机构信息

Department of Pediatrics, University of Virginia, Charlottesville, Virginia, USA.

出版信息

J Adolesc Health. 2002 Dec;31(6 Suppl):192-200. doi: 10.1016/s1054-139x(02)00485-8.

Abstract

Somatic growth and maturation are influenced by a number of factors that act independently or in concert to modify an individual's genetic potential. The secular trend in height and adolescent development is further evidence for the significant influence of environmental factors on an individual's genetic potential for linear growth. Nutrition, including energy and specific nutrient intake, is a major determinant of growth. Paramount to normal growth is the general health and well-being of an individual; in fact, normal growth is a strong testament to the overall good health of a child. More recently the effect of physical activity and fitness on linear growth, especially among teenage athletes, has become a topic of interest. Puberty is a dynamic period of development marked by rapid changes in body size, shape, and composition, all of which are sexually dimorphic. One of the hallmarks of puberty is the adolescent growth spurt. Body compositional changes, including the regional distribution of body fat, are especially large during the pubertal transition and markedly sexually dimorphic. The hormonal regulation of the growth spurt and the alterations in body composition depend on the release of the gonadotropins, leptin, the sex-steroids, and growth hormone. It is very likely that interactions among these hormonal axes are more important than their main effects, and that alterations in body composition and the regional distribution of body fat actually are signals to alter the neuroendocrine and peripheral hormone axes. These processes are merely magnified during pubertal development but likely are pivotal all along the way from fetal growth to the aging process.

摘要

体细胞生长和成熟受到多种因素的影响,这些因素单独或共同作用,以改变个体的遗传潜力。身高和青少年发育的长期趋势进一步证明了环境因素对个体线性生长遗传潜力的重大影响。营养,包括能量和特定营养素的摄入,是生长的主要决定因素。个体的总体健康状况对正常生长至关重要;事实上,正常生长有力地证明了儿童的整体健康状况良好。最近,身体活动和健康状况对线性生长的影响,尤其是在青少年运动员中,已成为一个受关注的话题。青春期是一个动态的发育阶段,其特征是身体大小、形状和组成的快速变化,所有这些都是两性异形的。青春期的标志之一是青少年生长突增。身体成分的变化,包括身体脂肪的区域分布,在青春期过渡期间尤为显著,且明显存在两性差异。生长突增的激素调节和身体成分的改变取决于促性腺激素、瘦素、性类固醇和生长激素的释放。这些激素轴之间的相互作用很可能比它们的主要作用更重要,而且身体成分的改变和身体脂肪的区域分布实际上是改变神经内分泌和外周激素轴的信号。这些过程在青春期发育期间只是被放大了,但从胎儿生长到衰老过程可能一直都起着关键作用。

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