Moser David J, Benjamin Michelle L, Bayless John D, McDowell Bradley D, Paulsen Jane S, Bowers Wayne A, Arndt Stephan, Andersen Arnold E
Department of Psychiatry, University of Iowa College of Medicine, Iowa City, Iowa 52240, USA.
Int J Eat Disord. 2003 Jan;33(1):64-70. doi: 10.1002/eat.10108.
This study was conducted to determine whether neuropsychological dysfunction associated with anorexia nervosa resolves with inpatient treatment.
Subjects were 28 women being treated for anorexia nervosa. Main study variables included body mass index (BMI), Beck Depression Inventory-II, and neuropsychological test scores. Subjects were tested at admission and discharge.
Neuropsychological functioning improved across the course of treatment, with significant changes on tests of memory and psychomotor speed. This improvement was not significantly associated with change in BMI or with the other variables that were studied.
Patients with anorexia nervosa exhibit subtle neuropsychological dysfunction, which resolves at least partially during treatment. This improvement does not appear to be associated with an increase in BMI. However, it is possible that BMI is not a sufficiently sensitive indicator of nutritional status or that longer-term follow-up is necessary to reveal the nutrition-cognition relationship that we were seeking.
本研究旨在确定神经性厌食症相关的神经心理功能障碍在住院治疗后是否会得到缓解。
研究对象为28名正在接受神经性厌食症治疗的女性。主要研究变量包括体重指数（BMI）、贝克抑郁量表第二版以及神经心理测试分数。研究对象在入院时和出院时接受测试。
在治疗过程中，神经心理功能有所改善，在记忆和心理运动速度测试方面有显著变化。这种改善与BMI的变化或所研究的其他变量没有显著关联。
神经性厌食症患者表现出轻微的神经心理功能障碍，在治疗期间至少会部分缓解。这种改善似乎与BMI的增加无关。然而，有可能BMI并不是营养状况的足够敏感指标，或者需要更长时间的随访来揭示我们所探寻的营养与认知之间的关系。
