Heikura Ulla, Taanila Anja, Olsen Päivi, Hartikainen Anna-Liisa, von Wendt Lennart, Järvelin Marjo-Riitta
University of Oulu, Department of Public Health Science and General Practice, Finland.
Am J Ment Retard. 2003 Jan;108(1):19-31. doi: 10.1352/0895-8017(2003)108<0019:TCIIAP>2.0.CO;2.
We followed two separate, genetically homogeneous cohorts of children born in 1966 (n = 11,965) and 1985-1986 (n = 9,432) in Northern Finland to determine temporal changes in the incidence and prevalence of subcategories of intellectual disability within the same geographic area. The children were followed up to the age of 11.5 years. Similar study design, data ascertainment methods, and definition of intellectual disability were used. There was no change in the total incidence (12.62/1,000 in each) or in total prevalence (11.03/1,000 vs. 11.23/1,000) of intellectual disability. However, in the subcategories of intellectual disability, there was a shift from severe and moderate towards mild; whereas profound intellectual disability remained at the same level. The temporal changes followed generally similar patterns by gender.
我们追踪了芬兰北部1966年出生的两组独立的、基因同质的儿童队列(n = 11,965)以及1985 - 1986年出生的儿童队列(n = 9,432),以确定同一地理区域内智力残疾亚类的发病率和患病率随时间的变化。这些儿童被随访至11.5岁。采用了相似的研究设计、数据确定方法以及智力残疾的定义。智力残疾的总发病率(每组均为12.62/1000)和总患病率(分别为11.03/1000和11.23/1000)均无变化。然而,在智力残疾亚类中,出现了从重度和中度向轻度的转变;而极重度智力残疾保持在同一水平。按性别划分,随时间的变化总体上遵循相似的模式。