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[外侧膝状体兴奋发生器定位的光原性癫痫(决定性调度站现象)]

[Photogenic epilepsy with localization of the generator of excitation in the lateral geniculate body (the phenomenon of a determining dispatch station)].

作者信息

Kryzhanovskiĭ G N, Rekhtman M B, Konnikov B A

出版信息

Biull Eksp Biol Med. 1976 Jan;81(1):22-5.

PMID:1247668
Abstract

The photogenic seizure syndrome was produced in experiments on rats and cats by injection of purified tetanus toxin into the lateral geniculate body (LGB). The seizures followed light stimulus or arose spontaneously. At the intervals between the attacks every light stimulus provoked a specific photojerk. Disturbance of the inhibitory mechanisms by tetanus toxin proved to result in a rise in the LGB of a generator of pathologically enhanced excitation underlying the hyperactive determinative dispatch station causing the described photogenic epilepsy.

摘要

通过向大鼠和猫的外侧膝状体(LGB)注射纯化的破伤风毒素,在实验中诱发了光发性癫痫综合征。癫痫发作跟随光刺激或自发出现。在发作间隔期间,每次光刺激都会引发特定的光阵挛。事实证明,破伤风毒素对抑制机制的干扰会导致LGB中一个病理性增强兴奋的发生器增加,该发生器位于导致所述光发性癫痫的过度活跃决定性调度站之下。

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