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[成人斯蒂尔病——1例女性患者的病例报告及文献复习]

[Still's disease in adulthood--case report of a female patient and review of the literature].

作者信息

Morović-Vergles Jadranka, Galesić Kresimir, Seferović Maida, Skobić Nada

机构信息

Klinicku imunologiju i reumatologiju, Klinika za unutarnje bolesti, KB Dubrava, Zagreb.

出版信息

Reumatizam. 2002;49(1):29-32.

Abstract

A 29-year old women with adult onset Still's disease (AOSD) was presented. On addmision to hospital the patient was febrile, with sore throat, arthralgia/arthritis and myalgia. The patient had lymphadenopathy on the neck, and laboratory findings showed leukocytosis with neutrophilia, accelarated erythrocyte sedimation rate (ESR), increased reactants of acute inflammation and normocytic anemia. During the diagnostic process, infectious, hematologic and neoplastic diseases were ruled out and the diagnosis of AOSD was made. The therapy with metilprednisolone 1 mg/kg of body weight was started. One month latter, the clinical status of the patient improved as well as laboratory findings. The dose of steroids was tappered to 16 mg per day. After 6 months of therapy, steroids were stopped and patient was followed further one year and she was free of symptoms of disease.

摘要

一名29岁成年起病的斯蒂尔病(AOSD)女性患者前来就诊。入院时患者发热,伴有咽痛、关节痛/关节炎和肌痛。患者颈部有淋巴结病,实验室检查结果显示白细胞增多伴中性粒细胞增多、红细胞沉降率(ESR)加快、急性炎症反应物增加以及正细胞性贫血。在诊断过程中,排除了感染性、血液学和肿瘤性疾病,确诊为AOSD。开始使用甲泼尼龙,剂量为1毫克/千克体重。一个月后,患者的临床状况以及实验室检查结果均有所改善。类固醇剂量逐渐减至每日16毫克。治疗6个月后,停用类固醇,对患者进一步随访一年,她没有疾病症状。

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