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[肾上腺素能结构在脑循环控制中的作用]

[The role of adrenergic structures in the control of cerebral circulation].

作者信息

Bugaev S A

出版信息

Biull Eksp Biol Med. 1976 Jan;81(1):9-12. doi: 10.1007/BF00800151.

Abstract

A study of the cerebral blood flow carried out by the thermoelectric method demonstrated that stimulation of the cervical sympathetic nerve led to marked changes in the cerebral blood supply. The blood flow changes were two-stage in character: an initial slight increase changed to a decrease below the initial level. Pharmacological analysis with the use of alpha- and beta-adrenoblockers showed a constrictor reaction of the cerebral vessels to be caused by excitation of the alpha-adrenoreactive structures, and the dilatator reaction - by the beta-adrenoreactive structures. An opinion is put forward on a possible mechanism of these changes.

摘要

一项采用热电法进行的脑血流量研究表明,刺激颈交感神经会导致脑供血发生显著变化。血流变化具有两阶段特征:最初的轻微增加随后转变为低于初始水平的减少。使用α和β肾上腺素能阻滞剂进行的药理学分析表明,脑血管的收缩反应是由α肾上腺素能反应结构的兴奋引起的,而扩张反应则是由β肾上腺素能反应结构引起的。文中提出了这些变化可能的机制。

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