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肾上腺素能结构在大脑循环功能控制中的作用。

Role of adrenergic structures in functional control over the cerebral circulation.

作者信息

Bugaev S A

出版信息

Neurosci Behav Physiol. 1978 Jul-Sep;9(3):262-5. doi: 10.1007/BF01187185.

DOI:10.1007/BF01187185
PMID:224339
Abstract

An investigation of the cerebral circulation by the thermoelectric method showed that stimulation of the cervical sympathetic nerve leads to considerable changes in the blood supply to the brain. The changes in blood flow are biphasic in character: An initial small increase is followed by a decrease below the original level. Pharmacological analysis with alpha and beta adreno-blockers showed that the constrictor response of the cerebral vessels is due to excitation of alpha-adrenergic structures and the dilator response to excitation of beta-adrenergic structures. A possible mechanism of these changes is postulated.

摘要

通过热电法对脑循环进行的一项研究表明,刺激颈交感神经会导致脑供血发生显著变化。血流变化具有双相性:最初有一个小幅度的增加,随后会降至原始水平以下。使用α和β肾上腺素能阻滞剂进行的药理学分析表明,脑血管的收缩反应是由于α肾上腺素能结构的兴奋,而扩张反应则是由于β肾上腺素能结构的兴奋。推测了这些变化的一种可能机制。

相似文献

1
Role of adrenergic structures in functional control over the cerebral circulation.肾上腺素能结构在大脑循环功能控制中的作用。
Neurosci Behav Physiol. 1978 Jul-Sep;9(3):262-5. doi: 10.1007/BF01187185.
2
[The role of adrenergic structures in the control of cerebral circulation].[肾上腺素能结构在脑循环控制中的作用]
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3
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Acta Physiol Scand. 1981 May;112(1):101-3. doi: 10.1111/j.1748-1716.1981.tb06789.x.
4
[Effect of blockade of the adrenergic structures of the hypothalamus on thermoregulatory reactions].
Fiziol Zh SSSR Im I M Sechenova. 1979 Jan;65(1):40-5.
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Acta Physiol Pharmacol Bulg. 1976;2(1):30-8.
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Acta Physiol Scand. 1980 Jan;108(1):77-83. doi: 10.1111/j.1748-1716.1980.tb06502.x.
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[Role of adrenergic mechanisms in the cerebrovascular effect of thyroliberin].[肾上腺素能机制在促甲状腺素释放激素脑血管效应中的作用]
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本文引用的文献

1
A study of the adrenotropic receptors.促肾上腺受体的研究。
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2
Cerebral sympathetic vasoconstriction and EEG.脑交感神经血管收缩与脑电图
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7
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Vestn Akad Med Nauk SSSR. 1973;28(12):38-40.
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[The mechanism of the influence of the cervical sympathetic nerves on cerebral blood supply].
Fiziol Zh SSSR Im I M Sechenova. 1972 Jul;58(7):1001-10.
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The influence of sympathetic nervous activity on cerebral blood flow.交感神经活动对脑血流量的影响。
Arch Neurol. 1972 Jul;27(1):1-6. doi: 10.1001/archneur.1972.00490130003001.
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Adrenergic mechanisms in the cerebral vascular bed.
Experientia. 1973 Jun 15;29(6):675-6. doi: 10.1007/BF01944766.