妊娠期的性类固醇与单胺代谢
Sexual steroids and monamine metabolism during gestation.
作者信息
Parvez S, Raza-Bukhari A, Harvez H
出版信息
Experientia. 1976 Jan 15;32(1):118-20. doi: 10.1007/BF01932658.
PMID:1248573
Abstract
The experiments show influence of progesterone and estradiol on regulation of enzymes of monamine metabolism, MAO and COMP during pregnancy. Both the hormones inhibit enzymes MAO and COMPT in the adrenals when determined at 0 h parturition. Estradiol has stronger inhibitory effect than progesterone. The results provide evidence for important endocrine implication during pregnancy for processes of monamine regulation.
摘要
实验表明，孕期黄体酮和雌二醇对单胺代谢酶（单胺氧化酶和儿茶酚-O-甲基转移酶）的调节有影响。在分娩0小时测定时，这两种激素均抑制肾上腺中的单胺氧化酶和儿茶酚-O-甲基转移酶。雌二醇的抑制作用比黄体酮更强。这些结果为孕期单胺调节过程中的重要内分泌影响提供了证据。
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