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不同沐浴介质对大鼠和豚鼠肠道短路电流的影响。

Effect of different bathing media on the short-circuit current across the intestine of the rat and guinea-pig.

作者信息

Mateu L, Robinson J W

出版信息

Experientia. 1976 Jan 15;32(1):62-4. doi: 10.1007/BF01932624.

DOI:10.1007/BF01932624
PMID:1248592
Abstract

The changes in short-circuit current occurring when one or both solutions bathing the intestine of rat or guinea-pig mounted in flux chambers were recorded. The results with the guinea-pig can be explained in terms of diffusion potentials arising from the ionic replacements, and an electrogenic sodium pump, sensitive to ouabain, in the contraluminal membrane of the cell. In the rat, the situation is more complicated, and the enterocyte probably possesses an electrogenic sodium pump in the brush-border membrane.

摘要

记录了将大鼠或豚鼠的肠道置于通量室中,当浸泡肠道的一种或两种溶液发生变化时短路电流的变化情况。豚鼠实验的结果可以用离子替代产生的扩散电位以及细胞对哇巴因敏感的对腔膜中的生电钠泵来解释。在大鼠中,情况更为复杂,肠上皮细胞可能在刷状缘膜中拥有生电钠泵。

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本文引用的文献

1
Junction potentials, electrode standard potentials, and other problems in interpreting electrical properties of membranes.电生理学:膜的电学性质的解释中的接头电位、电极标准电位和其他问题。
J Membr Biol. 1970 Dec;3(1):93-122. doi: 10.1007/BF01868010.
2
ION TRANSPORT IN ISOLATED RABBIT ILEUM. I. SHORT-CIRCUIT CURRENT AND NA FLUXES.离体兔回肠中的离子转运。I. 短路电流与钠通量
J Gen Physiol. 1964 Jan;47(3):567-84. doi: 10.1085/jgp.47.3.567.
3
Species differences in the intestinal response to sulphate ions.肠道对硫酸根离子反应的种属差异。
FEBS Lett. 1969 Oct 21;5(2):157-160. doi: 10.1016/0014-5793(69)80319-4.
4
Diffusion potentials across the small intestine.小肠上的扩散电位。
Nature. 1966 Oct 8;212(5058):189-90. doi: 10.1038/212189a0.
5
Studies on the mechanism of intestinal absorption of sugars. 8. Cation inhibition of active sugar transport and 22Na influx into hamster small intestine, in vitro.
Biochim Biophys Acta. 1965 Jul 22;102(2):423-35. doi: 10.1016/0926-6585(65)90132-9.
6
Inhibition of active intestinal sugar transport by digitalis.洋地黄对肠道活性糖转运的抑制作用。
Am J Physiol. 1965 Sep;209(3):467-72. doi: 10.1152/ajplegacy.1965.209.3.467.
7
Effects of pH and polyvalent cations on the selective permeability of gall-bladder epithelium to monovalent ions.pH值和多价阳离子对胆囊上皮对单价离子选择性通透性的影响。
Biochim Biophys Acta. 1968 Aug;163(1):57-74. doi: 10.1016/0005-2736(68)90033-3.
8
Effect of transported solutes on membrane potentials in bullfrog small intestine.转运溶质对牛蛙小肠膜电位的影响。
Am J Physiol. 1971 Jul;221(1):194-201. doi: 10.1152/ajplegacy.1971.221.1.194.
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The loss of intestinal transport capacity following preincubation in sodium-free media in vitro.体外在无钠培养基中预孵育后肠道转运能力的丧失。
Pflugers Arch Gesamte Physiol Menschen Tiere. 1967;294(2):182-200. doi: 10.1007/BF00363605.
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Electrolyte secretion by the guinea pig ileum in vitro.豚鼠离体回肠的电解质分泌
Am J Physiol. 1972 Sep;223(3):531-7. doi: 10.1152/ajplegacy.1972.223.3.531.