Iimura Akiko, Yoshihara Shigemi, Arisaka Osamu
Department of Pediatrics, Dokkyo University School of Medicine, Japan.
Arerugi. 2002 Nov;51(11):1131-4.
Interrupter respiratory resistance (Rint) is a new lung function test for measuring airway resistance. We investigated the utility of the Rint lung function test in pediatric patients with asthma. Thirty seven asthmatic patients with mild or moderate asthma attack (asthma group) and 9 healthy children (control group) were enrolled in the study, and the utility of the Ring test was compared with that of the PEF lung function test. Rint and PEF were measured after the inhalation of saline or beta(2) stimulant, and the values for the asthma and control groups were compared. The rint and PEF values did not change after the inhalation of saline, but both values improved after the inhalation of beta(2) stimulant in the asthma group. In the control group, the PEF and Rint values measured after saline or beta(2) stimulant were not significantly different. Rint measurements may be more useful than PEF tests for evaluating therapeutic responses to mild asthma attacks in children. These findings suggest that Rint is a useful respiratory function test for evaluating children with asthma.
间断呼吸阻力(Rint)是一种用于测量气道阻力的新肺功能测试。我们研究了Rint肺功能测试在小儿哮喘患者中的实用性。37例轻度或中度哮喘发作的哮喘患者(哮喘组)和9名健康儿童(对照组)纳入本研究,并将Rint测试的实用性与呼气峰流量(PEF)肺功能测试进行比较。在吸入盐水或β₂激动剂后测量Rint和PEF,并比较哮喘组和对照组的值。吸入盐水后Rint和PEF值未改变,但哮喘组吸入β₂激动剂后两个值均改善。在对照组中,盐水或β₂激动剂后测量的PEF和Rint值无显著差异。对于评估儿童轻度哮喘发作的治疗反应,Rint测量可能比PEF测试更有用。这些发现表明,Rint是评估哮喘儿童的一种有用的呼吸功能测试。