Holzmann David, Funke Guido, Linder Thomas, Nadal David
Department of Otorhinolaryngology, University of Zurich, Switzerland.
Pediatr Infect Dis J. 2002 Dec;21(12):1124-6. doi: 10.1097/00006454-200212000-00007.
The recently described coryneform bacteria and were first detected in the middle ear of patients with acute otitis media and chronic otitis media. Whether these bacteria play an essential role in the pathogenesis of otitis media with effusion (OME) is unclear.
In a prospective study 60 children with OME and 205 controls were evaluated to determine the incidence of and. Swabs from the external auditory canal (EAC) and the middle ear effusion (MEE) of OME children undergoing tympanotomy, ventilation tube insertion or both were cultured. Swabs from the EAC from healthy children served as controls.
In control children was found in EAC swabs from 23 of 205 (11.2%) and in 32 of 205 (15.6%). was isolated from 14 of 60 (23.3%) OME patients from the EAC only and in 6 of 60 (10.0%) OME patients from both EAC and MEE. was isolated in 2 of 60 (3.3%) from the EAC only and in 1 of 60 (1.7%) from both EAC and MEE. In no patient did or grow exclusively from MEE.
and may be part of the normal bacterial flora of the EAC in some children. Neither organism seems to cause OME in children.
最近描述的棒状杆菌最初是在急性中耳炎和慢性中耳炎患者的中耳中检测到的。这些细菌是否在分泌性中耳炎(OME)的发病机制中起重要作用尚不清楚。
在一项前瞻性研究中,对60例OME患儿和205例对照进行评估,以确定[具体细菌名称未给出]的发生率。对接受鼓膜切开术、插入通气管或两者皆做的OME患儿的外耳道(EAC)拭子和中耳积液(MEE)进行培养。健康儿童的EAC拭子作为对照。
在对照儿童中,205例中有23例(11.2%)的EAC拭子中发现[第一种细菌名称未给出],205例中有32例(15.6%)发现[第二种细菌名称未给出]。仅从EAC中分离出[第一种细菌名称未给出]的OME患者有60例中的14例(23.3%),从EAC和MEE中均分离出的有60例中的6例(10.0%)。仅从EAC中分离出[第二种细菌名称未给出]的有60例中的2例(3.3%),从EAC和MEE中均分离出的有60例中的1例(1.7%)。没有患者的[第一种细菌名称未给出]或[第二种细菌名称未给出]仅从MEE中生长。
[第一种细菌名称未给出]和[第二种细菌名称未给出]可能是一些儿童EAC正常细菌菌群的一部分。这两种微生物似乎都不会导致儿童患OME。