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耳炎泰氏菌的代谢和基因序列变异表明其在外耳感染中的适应性和致病性:系统评价。

Metabolism and gene sequence variation in Turicella otitidis implies its adaptability and pathogenicity in extra-otic infection: a systematic review.

机构信息

Clinical Laboratory Sciences Program, School of Health Profession, Stony Brook University, Stony Brook, NY, USA.

Department of Neuroscience and Behavior, Stony Brook University, Stony Brook, NY, USA.

出版信息

BMC Infect Dis. 2023 Oct 27;23(1):735. doi: 10.1186/s12879-023-08721-y.

DOI:10.1186/s12879-023-08721-y
PMID:37891485
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10612267/
Abstract

Turicella otitidis belongs to the Corynebacteriaceae family and is a normal inhabitant of the ear and exists in a commensal relationship with its host. In children, T. otitidis is frequently associated with otitis media. The emergence of Turicella otitidis as a pathogen is concerning, particularly due to the limited availability of data on its pathogenic properties. The objective of this study is to conduct a systematic review of T. otitidis infections occurring in both the ear and other anatomical sites, and to summarize the differences in metabolism and genome sequences between isolates obtained from the ear and blood.

摘要

豚鼠耳炎菌属于棒状杆菌科,是耳朵的正常寄居者,与宿主保持共生关系。在儿童中,豚鼠耳炎菌常与中耳炎有关。豚鼠耳炎菌作为病原体的出现令人担忧,特别是因为关于其致病特性的数据有限。本研究的目的是对发生在耳部和其他解剖部位的豚鼠耳炎菌感染进行系统综述,并总结从耳部和血液中分离得到的菌株在代谢和基因组序列上的差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4719/10612267/76c4fc13fd71/12879_2023_8721_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4719/10612267/cba5256d372e/12879_2023_8721_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4719/10612267/76c4fc13fd71/12879_2023_8721_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4719/10612267/cba5256d372e/12879_2023_8721_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4719/10612267/76c4fc13fd71/12879_2023_8721_Fig2_HTML.jpg

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