Shahriar Farshid M, Clark Edward G, Janzen Eugene, West Keith, Wobeser Gary
Department of Veterinary Pathology, Western College of Veterinary Medicine, 52 Campus Drive, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5B4.
Can Vet J. 2002 Nov;43(11):863-8.
Chronic, antibiotic-resistant pneumonia, sometimes with concurrent polyarthritis, occurs in feedlot cattle in western Canada. The prevalence of Mycoplasma bovis, bovine viral diarrhea virus, and Haemophilus somnus was determined by using immunohistochemical staining of lung and heart tissue from 2 groups of animals with this history. Mycoplasma bovis antigen was present in 44/48 cases submitted between 1995 and 1998 (retrospective group) and 15/16 of cases from 1999 (prospective group), and was associated with pulmonary necrosis. Bovine viral diarrhea virus antigen was present in association with microscopic vascular lesions in 31/48 retrospective and 9/16 of prospective cases. Types Ib and II bovine viral diarrhea virus were isolated from 4/16 prospective cases. Haemophilus somnus antigen was present in heart, lung, or both of 15/48 retrospective and 8/16 prospective cases. The results suggest that there may be synergism between bovine viral diarrhea virus and M. bovis in this pneumonia with arthritis syndrome.
慢性、耐抗生素肺炎，有时并发多关节炎，发生于加拿大西部的育肥牛中。通过对两组有此病史动物的肺和心脏组织进行免疫组织化学染色，确定了牛支原体、牛病毒性腹泻病毒和睡眠嗜血杆菌的流行情况。在1995年至1998年提交的48例病例（回顾性组）中有44例以及1999年的16例病例（前瞻性组）中有15例存在牛支原体抗原，且其与肺坏死有关。在31/48例回顾性病例和9/16例前瞻性病例中，牛病毒性腹泻病毒抗原与微血管病变相关。从16例前瞻性病例中的4例分离出Ib型和II型牛病毒性腹泻病毒。在15/48例回顾性病例和8/16例前瞻性病例的心脏、肺或两者中存在睡眠嗜血杆菌抗原。结果表明，在这种伴有关节炎综合征的肺炎中，牛病毒性腹泻病毒和牛支原体之间可能存在协同作用。
