Katzenschlager Regina, Costa Durval, Gacinovic Svetislav, Lees Andrew J
National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
Neurology. 2002 Dec 24;59(12):1974-6. doi: 10.1212/01.wnl.0000037484.28297.66.
Isolated foot dystonia following exercise is a rare manifestation of early PD. It may precede the onset of parkinsonism by years and can be clinically indistinguishable from familial exercise-induced dystonia. The authors present a patient with dystonic claudication where dopamine transporter SPECT using (123)I-FP-CIT allowed early diagnosis of PD and enabled effective symptomatic treatment with a dopamine agonist.
运动后孤立性足部肌张力障碍是早期帕金森病的一种罕见表现。它可能在帕金森综合征发病前数年出现,临床上与家族性运动诱发性肌张力障碍难以区分。作者报告了一名患有肌张力障碍性跛行的患者,使用(123)I-FP-CIT的多巴胺转运体单光子发射计算机断层扫描(SPECT)实现了帕金森病的早期诊断,并通过多巴胺激动剂进行了有效的对症治疗。