Ma M, Barnes G, Pulliam J, Jezek D, Baumann R J, Berger J R
Department of Neurology, University of Kentucky College of Medicine, Lexington, KY 40536, USA.
Neurology. 2002 Dec 24;59(12):1994-7. doi: 10.1212/01.wnl.0000038948.09158.a7.
Graft-vs-host disease (GVHD) is a potentially treatable cause of progressive neurologic decline after bone marrow transplantation (BMT). The authors present histologic confirmation of CNS granulomatous angiitis in a child with chronic GVHD after BMT. Since cranial MRI showed only nonspecific findings, CNS vasculitis associated with GVHD after BMT may be underdiagnosed.