Haze Shinichiro, Sakai Keiko, Gozu Yoko
Product Development Center, Shiseido Co., Ltd., Hayabuchi, Yokohama, Japan.
Jpn J Pharmacol. 2002 Nov;90(3):247-53. doi: 10.1254/jjp.90.247.
We investigated the effects of fragrance inhalation on sympathetic activity in normal adult subjects using both power spectral analysis of blood pressure fluctuations and measurement of plasma catecholamine levels. Fragrance inhalation of essential oils, such as pepper oil, estragon oil, fennel oil or grapefruit oil, resulted in 1.5- to 2.5-fold increase in relative sympathetic activity, representing low frequency amplitude of systolic blood pressure (SBP-LF amplitude), compared with inhalation of an odorless solvent, triethyl citrate (P<0.05, each). In contrast, fragrance inhalation of rose oil or patchouli oil caused a 40% decrease in relative sympathetic activity (P<0.01, each). Fragrance inhalation of pepper oil induced a 1.7-fold increase in plasma adrenaline concentration compared with the resting state (P = 0.06), while fragrance inhalation of rose oil caused a 30% decrease in adrenaline concentration (P<0.01). Our results indicate that fragrance inhalation of essential oils may modulate sympathetic activity in normal adults.
我们通过对血压波动进行功率谱分析以及测量血浆儿茶酚胺水平，研究了吸入香料对正常成年受试者交感神经活动的影响。与吸入无味溶剂柠檬酸三乙酯相比，吸入胡椒油、龙蒿油、茴芹油或葡萄柚油等香精油会使相对交感神经活动增加1.5至2.5倍，表现为收缩压的低频幅度（SBP-LF幅度）（每组P<0.05）。相比之下，吸入玫瑰油或广藿香精油会使相对交感神经活动降低40%（每组P<0.01）。与静息状态相比，吸入胡椒油会使血浆肾上腺素浓度增加1.7倍（P = 0.06），而吸入玫瑰油会使肾上腺素浓度降低30%（P<0.01）。我们的结果表明，吸入香精油可能会调节正常成年人的交感神经活动。
