Henning H, Schuff-Werner P
Med Klin. 1976 Jan 23;71(4):163-7.
By radioimmuno-assay we found HBSAg in 4.2% and HBS-Antibodies in 60% in a group of 120 partners of patients with HBSAg-positive chronic liver diseases. The high incidence of HBS-antibodies in the group of partners is supposed to be due to a transmission of very small amounts of HBSAg containing material in a way of occult immunisation. There were no significant relations to the sex of the partners nor the age of the patients or the activity and duration of the disease. Our clinical investigations do not support demands for a strict isolation of patients with positive HBSAg findings nor do they imply that health-care workers should change their professions in case of HBS-antigenemia.
通过放射免疫测定法,我们在一组120名乙肝表面抗原(HBsAg)阳性慢性肝病患者的伴侣中发现,4.2%的人有HBsAg,60%的人有乙肝表面抗体(HBs抗体)。伴侣组中HBs抗体的高发生率被认为是由于极少量含HBsAg物质以隐匿免疫的方式传播所致。这与伴侣的性别、患者的年龄以及疾病的活动程度和持续时间均无显著关系。我们的临床研究不支持对HBsAg检测呈阳性的患者进行严格隔离的要求,也不意味着医护人员在出现HBs抗原血症时应更换职业。