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一项比较硬膜外镇痛下延迟用力与立即用力对分娩方式和大便失禁影响的随机临床试验。

A randomised clinical trial comparing the effects of delayed versus immediate pushing with epidural analgesia on mode of delivery and faecal continence.

作者信息

Fitzpatrick Myra, Harkin Rosemary, McQuillan Katherine, O'Brien Conor, O'Connell P Ronan, O'Herlihy Colm

机构信息

Department of Obstetrics and Gynaecology, National Maternity Hospital, University College Dublin, Ireland.

出版信息

BJOG. 2002 Dec;109(12):1359-65. doi: 10.1046/j.1471-0528.2002.02109.x.

Abstract

OBJECTIVE

To assess the effects of delayed vs immediate pushing in second stage of labour with epidural analgesia on delivery outcome, postpartum faecal continence and postpartum anal sphincter and pudendal nerve function.

DESIGN

Prospective, randomised, controlled trial.Tertiary referral maternity teaching hospital.

POPULATION

One hundred and seventy nulliparous women randomised at full dilatation to immediate or delayed pushing.

METHODS

A total of 178 nulliparous women, all with continuous epidural analgesia, were randomised at full cervical dilatation, but before the fetal head had reached the pelvic floor, to either immediate pushing or 1 hour delayed pushing. Labour outcome was analysed and all women underwent postpartum assessment of anal sphincter function, including anal manometry. Those women who had a normal delivery underwent neurophysiology studies, while those women who had an instrumental delivery underwent endoanal ultrasound.

MAIN OUTCOME MEASURES

Mode of delivery; altered faecal continence.

RESULTS

Ninety women were randomised to immediate pushing and 88 to delayed pushing. The spontaneous delivery rate was 56% (50/90) in the immediate pushing group and 52% (46/88) in the delayed pushing group. Mean duration of labour for the immediate pushing group was 427 minutes compared with 480 minutes for the delayed pushing group (P = 0.005). Eighty-four percent (76/90) of women in the immediate pushing group received oxytocin to augment labour, 21/76 (28%) in the second stage only. Eighty-one percent (71/88) of women in the delayed pushing group received oxytocin to augment labour, 22/71 (31%) in the second stage only. Fetal outcome did not differ between the two groups. Episiotomy rates were 73% and 69% in the immediate pushing and delayed pushing groups, respectively. 26% (23/90) of the immediate pushing group and 38% (33/88) of the delayed pushing group complained of altered faecal continence after delivery (NS). Manometry, ultrasound and neurophysiology studies did not differ significantly between the two groups. Overall, 55% of women after instrumental delivery had endosonographic evidence of damage to the external anal sphincter, while 36% of women after spontaneous delivery had abnormal neurophysiology studies.

CONCLUSIONS

Rates of instrumental delivery were similar following immediate and delayed pushing, in association with epidural analgesia. Delayed pushing prolonged labour by 1 hour but did not result in significantly higher rates of altered continence or anal sphincter injury, when compared with immediate pushing.

摘要

目的

评估硬膜外镇痛分娩第二产程中延迟用力与立即用力对分娩结局、产后大便失禁及产后肛门括约肌和阴部神经功能的影响。

设计

前瞻性、随机、对照试验。三级转诊妇产教学医院。

研究对象

170例初产妇,在宫口开全时随机分为立即用力组或延迟用力组。

方法

共有178例初产妇,均采用持续硬膜外镇痛,在宫颈完全扩张但胎头未达盆底前,随机分为立即用力组或延迟1小时用力组。分析分娩结局,所有产妇均接受产后肛门括约肌功能评估,包括肛门测压。顺产的产妇接受神经生理学研究,助产分娩的产妇接受经肛门超声检查。

主要观察指标

分娩方式;大便失禁改变。

结果

90例产妇被随机分配到立即用力组,88例被分配到延迟用力组。立即用力组自然分娩率为56%(50/90),延迟用力组为52%(46/88)。立即用力组的平均产程为427分钟,延迟用力组为480分钟(P = 0.005)。立即用力组84%(76/90)的产妇使用缩宫素加强宫缩,其中仅21/76(28%)在第二产程使用。延迟用力组81%(71/88)的产妇使用缩宫素加强宫缩,其中仅22/71(31%)在第二产程使用。两组胎儿结局无差异。立即用力组和延迟用力组的会阴切开率分别为73%和69%。立即用力组26%(23/90)和延迟用力组38%(33/88)的产妇产后抱怨大便失禁改变(无统计学差异)。两组间测压、超声和神经生理学研究无显著差异。总体而言,助产分娩后55%的产妇经超声检查有肛门外括约肌损伤证据,顺产产妇中36%神经生理学研究异常。

结论

硬膜外镇痛下,立即用力和延迟用力后的助产分娩率相似。与立即用力相比,延迟用力使产程延长1小时,但并未导致大便失禁改变或肛门括约肌损伤发生率显著升高。

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