Beebe C G, Schemmel R, Michkelsen O
Proc Soc Exp Biol Med. 1976 Feb;151(2):395-9. doi: 10.3181/00379727-151-39219.
In the first experiment, weanling rats were fed a grain ration or one of three semipurified diets high in fat, sucrose, or cornstarch. Rats in each dietary group were divided into two subgroups, one of which drank distilled deionized water whereas the other group drank 2% NaCl solution. Blood pressure and sodium intake were individually measured for each rat at weekly intervals for a 10-week period. Rats receiving the salt solution had higher mean blood pressures (127-178 mmHg) than rats offered distilled water (108-127 mmHg). When drinking solutions were the same, more severe rises in blood pressure occurred in rats fed the semipurified diets than in those rats fed grain. In a second experiment, rats were fed one of the four diets used in the first experiment; however, they received a 1% NaCl drinking solution for 9 weeks followed by a 1.5% NaCl solution for an additional 9 weeks. At Week 18, pressures among these groups of rats ranged from 136-140 mmHg, regardless of diet.
在第一个实验中，给断奶大鼠喂食谷物日粮或三种高脂肪、高蔗糖或高玉米淀粉的半纯化日粮之一。每个饮食组的大鼠被分为两个亚组，其中一个亚组饮用蒸馏去离子水，而另一组饮用2%的氯化钠溶液。在为期10周的时间里，每周对每只大鼠分别测量血压和钠摄入量。饮用盐溶液的大鼠的平均血压（127 - 178毫米汞柱）高于饮用蒸馏水的大鼠（108 - 127毫米汞柱）。当饮用溶液相同时，喂食半纯化日粮的大鼠血压升高比喂食谷物的大鼠更严重。在第二个实验中，给大鼠喂食第一个实验中使用的四种日粮之一；然而，它们先饮用1%的氯化钠溶液9周，然后再饮用1.5%的氯化钠溶液9周。在第18周时，这些大鼠组的血压在136 - 140毫米汞柱之间，与饮食无关。
