肿瘤库：为了患者利益而妥善保管的珍贵资源。

Tumour banks: well-guarded treasures in the interest of patients.

作者信息

Oosterhuis J Wolter, Coebergh Jan Willem, van Veen Evert-Ben

机构信息

Josephine Nefkens Institute, Department of Pathology, Erasmus MC, Rotterdam 3000 DR, The Netherlands.

出版信息

Nat Rev Cancer. 2003 Jan;3(1):73-7. doi: 10.1038/nrc973.

DOI:10.1038/nrc973

PMID:12509769

Abstract

In order for the genomics revolution to change how we diagnose, categorize and treat cancer, scientists and clinicians must have access to tumour samples. There has therefore never been a better time to create banks of tumour tissue. Collecting and storing tumour samples and their associated data, however, creates numerous methodological, ethical, legal and technical problems. How can we leap these hurdles in a responsible manner and still make full use of the wealth of information that can be obtained from them?

摘要

为了让基因组学革命改变我们诊断、分类和治疗癌症的方式，科学家和临床医生必须能够获取肿瘤样本。因此，现在正是创建肿瘤组织库的最佳时机。然而，收集和存储肿瘤样本及其相关数据会带来许多方法学、伦理、法律和技术问题。我们如何以负责任的方式跨越这些障碍，同时充分利用从这些样本中获得的丰富信息呢？