Kaiser Amy S, Ferris Lorraine E, Pastuszak Anne L, Llewellyn-Thomas Hilary, Johnson Jo-Ann, Conacher Susan, Shaw B F
Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada.
J Obstet Gynaecol. 2002 May;22(3):246-55. doi: 10.1080/01443610220130508.
This study evaluates the effects of prenatal genetic group counselling on women's anxiety, decisional conflict and levels of knowledge. Participants (N=271) were aged 35 years and older. ANOVA results indicated that pre/postcounselling scores for anxiety did not change significantly, while decisional conflict decreased significantly (P<0.001). Pre/postcounselling scores on two different knowledge measures were analysed using 2x3 mixed ANOVAs for time by highest level of education and by having discussed prenatal diagnosis with one's health care provider. No potential interactions were statistically significant; time alone had a strong significant effect for both knowledge measures (P<0.01); P<0.01, respectively), suggesting that the effects of the counselling intervention were robust. Group genetic counselling is an effective method for education and decision support in the prenatal context, and may serve as a model for other clinical populations facing genetic screening decisions.
本研究评估了产前基因群体咨询对女性焦虑、决策冲突和知识水平的影响。参与者(N = 271)年龄在35岁及以上。方差分析结果表明,咨询前后焦虑得分无显著变化,而决策冲突显著降低(P<0.001)。对于两种不同的知识测量指标,通过2×3混合方差分析,按最高教育水平以及是否与医疗保健提供者讨论过产前诊断来分析咨询前后的得分。没有潜在的交互作用具有统计学意义;仅时间因素对两种知识测量指标都有强烈的显著影响(P<0.01;P<0.01),这表明咨询干预的效果是显著的。群体基因咨询是产前教育和决策支持的有效方法,可为面临基因筛查决策的其他临床人群提供范例。