Schauf C L
Biophys J. 1976 Mar;16(3):245-8. doi: 10.1016/S0006-3495(76)85684-6.
Values for the time constant of reactivation of the sodium conductance following depolarization sufficient to completely inactivate GNa have been compared over a 15 mV range of membrane potential with the time constants of inactivation during a depolarization prepulse. Over this range the reactivation time constants were consistently 30-50% larger than the inactivation time constants determined simultaneously at the same potential in the same axon. The data suggests that inactivation and reactivation do not occur by identical mechanisms, and therefore implies that there are at least three kinds of experimental procedures necessary to fully characterize the sodium inactivation process in any particular system.
在足以使钠电导完全失活的去极化后，钠电导再激活时间常数的值，已在15mV的膜电位范围内，与去极化预脉冲期间的失活时间常数进行了比较。在此范围内，再激活时间常数始终比在同一轴突中相同电位下同时测定的失活时间常数大30 - 50%。数据表明，失活和再激活并非通过相同机制发生，因此意味着，在任何特定系统中，要全面表征钠失活过程，至少需要三种实验程序。
