先天性风疹的预防
Prevention of congenital rubella.
作者信息
Welch J P
出版信息
Can Med Assoc J. 1977 Jul 23;117(2):151-6.
The vaccine of choice for rubella vaccination is considered to be RA 27/3, based on frequency of side effects, duration of immunity, antigenic potential and rate of reinfection by wild virus. The most appropriate individuals to be vaccinated are prepubertal schoolgirls and susceptible members of other high-risk groups, and a nationwide immunization program is suggested. Premarital determination of rubella-immune status should be mandatory for all women of childbearing age. A favourable cost/benefit ratio for rubella vaccination seems highly probable. The use of a rubella "fact sheet" to provide education and information for those at risk is strongly recommended.
基于副作用发生频率、免疫持续时间、抗原潜力和野生病毒再感染率，风疹疫苗接种的首选疫苗被认为是RA 27/3。最适合接种疫苗的人群是青春期前的女学生和其他高危人群中的易感者，建议开展全国性免疫计划。所有育龄妇女都应强制进行婚前风疹免疫状态测定。风疹疫苗接种的成本效益比似乎很可能是有利的。强烈建议使用风疹“情况说明书”为高危人群提供教育和信息。
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