淋巴管生成的新机制。
Lymphangiogenesis new mechanisms.
作者信息
Chang Lynn, Kaipainen Arja, Folkman Judah
机构信息
Department of Surgery, Harvard Medical School, and Surgical Research Laboratory, Children's Hospital, Boston, Massachusetts 02115, USA.
出版信息
Ann N Y Acad Sci. 2002 Dec;979:111-9. doi: 10.1111/j.1749-6632.2002.tb04872.x.
Abstract
A mouse model has been developed to study lymphangiogenesis dissociated from angiogenesis. bFGF implanted in a mouse cornea at a concentration below the threshold to induce angiogenesis potently induces lymphangiogenesis. This model has permitted a study of cellular and molecular mechanisms of lymphangiogenesis.
摘要
已开发出一种小鼠模型来研究与血管生成分离的淋巴管生成。以低于有效诱导血管生成阈值的浓度将碱性成纤维细胞生长因子（bFGF）植入小鼠角膜，可有效诱导淋巴管生成。该模型有助于研究淋巴管生成的细胞和分子机制。
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