Shearer T R, Ridlington J W
J Nutr. 1976 Apr;106(4):451-6. doi: 10.1093/jn/106.4.451.
The interaction of dietary fluoride and selenium in the hard and soft tissues of rats was studied by providing drinking solutions containing 50 ppm F, as NaF, alone or plus 1 or 3 ppm Se as one of the following selenium compounds: NaSeO3, Na2SeO4, DL-selenomethionine, or DL-selenocystine. The following parameters were measured: symptoms of selenium toxicity, soft tissue uptake of fluoride and selenium, histology of liver and kidney tissues, fluoride uptake into growing femur bones, and fluoride uptake onto calcified molar enamel. No evidence was found that fluoride interacted with any of the four selenium compounds.
通过提供含有50 ppm氟（以氟化钠形式）的饮用水溶液，单独使用或添加1或3 ppm硒（以下四种硒化合物之一：亚硒酸钠、硒酸钠、DL-硒代蛋氨酸或DL-硒代胱氨酸），研究了饮食中氟与硒在大鼠软硬组织中的相互作用。测量了以下参数：硒中毒症状、软组织对氟和硒的摄取、肝脏和肾脏组织的组织学、生长中的股骨对氟的摄取以及钙化磨牙牙釉质对氟的摄取。未发现氟与四种硒化合物中的任何一种发生相互作用的证据。
