Palmer Julie R, Rosenberg Lynn, Wise Lauren A, Horton Nicholas J, Adams-Campbell Lucile L
Slone Epidemiology Unit, Boston University School of Public Health, Mass 02215, USA.
Am J Public Health. 2003 Feb;93(2):299-306. doi: 10.2105/ajph.93.2.299.
This study assessed predictors of the onset of natural menopause in African American women.
We used mailed questionnaires to collect data at baseline in 1995 and during follow-up from Black Women's Health Study participants. Cox proportional hazards regression was used to assess potential predictors-including experiences of racism-of the onset of natural menopause among 17 070 women aged 35 to 55 years and premenopausal in 1995.
The hazard ratio (HR) was 1.43 for current smokers (95% confidence interval [CI] = 1.24, 1.66) and 1.21 (95% CI = 1.06, 1.38) for ex-smokers and significantly less for obese women and oral contraceptive users. Hazard ratios for most questions about racism were elevated by 10% to 30% but were not statistically significant.
Earlier onset of natural menopause among African American women is strongly associated with smoking and inversely associated with body mass index and oral contraceptive use.
本研究评估了非裔美国女性自然绝经 onset 的预测因素。
我们使用邮寄问卷在 1995 年基线时以及对黑人女性健康研究参与者进行随访期间收集数据。Cox 比例风险回归用于评估 1995 年年龄在 35 至 55 岁且处于绝经前的 17070 名女性中自然绝经 onset 的潜在预测因素,包括种族主义经历。
当前吸烟者的风险比(HR)为 1.43(95%置信区间[CI]=1.24,1.66),既往吸烟者为 1.21(95%CI = 1.06,1.38),肥胖女性和口服避孕药使用者的风险比显著更低。关于种族主义的大多数问题的风险比提高了 10%至 30%,但无统计学意义。
非裔美国女性自然绝经的提前 onset 与吸烟密切相关,与体重指数和口服避孕药的使用呈负相关。