Lyu Xiru, Huang Alison J, Kelman Alexa V, Tauman Riva, Kanaya Alka M, Dunietz Galit Levi
Consulting for Statistics, Computing and Analytics Research, University of Michigan, Ann Arbor, MI, USA.
Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Climacteric. 2025 Apr 3:1-8. doi: 10.1080/13697137.2025.2480584.
This study aimed to characterize menopause timing, type (natural or surgical) and symptoms in US-based South Asian women.
The study included 405 women of South Asian descent aged between 43 and 78 years who participated in the Mediators of Atherosclerosis in South Asians Living in America (MASALA) study. Menopause experiences were assessed with structured questionnaires. The study described sociodemographic, health and lifestyle characteristics and menopause symptoms by menopause stage, type (natural or surgical) and timing, and tested for differences using chi-square and Fisher's exact tests.
Most women (92%) were postmenopausal, and 7% reported surgical menopause. The mean recalled age at natural menopause was 48 years, and the median recalled age was 49 years. Nearly a third of women experienced premature/early menopause (age ≤45 years). Overall, women reported hot flashes of any intensity (from mild to extremely bothersome) in the past month (30%), urinary incontinence in the past 12 months (37%) and depressive symptoms (15%). Menopause symptoms varied by menopause timing and type (natural vs. surgical). Particularly, the point prevalence of bothersome hot flashes of any intensity in the past month, urinary leakage in the past 12 months and depressive symptoms in the past week was 28%, 37% and 14%, respectively, for women who had natural menopause, and 40%, 48% and 20%, respectively, for surgical menopause.
Women of South Asian ancestry reported an earlier recalled age at natural menopause than the average age of 52 years reported in the USA. The burden of hot flashes of any intensity, urinary and mood disturbances suggested distinct postmenopause experiences.
本研究旨在描述美国南亚裔女性的绝经时间、类型(自然绝经或手术绝经)及症状。
该研究纳入了405名年龄在43至78岁之间的南亚裔女性,她们参与了“美国南亚人动脉粥样硬化的中介因素”(MASALA)研究。通过结构化问卷评估绝经经历。该研究按绝经阶段、类型(自然绝经或手术绝经)和时间描述了社会人口统计学、健康和生活方式特征以及绝经症状,并使用卡方检验和费舍尔精确检验来检验差异。
大多数女性(92%)已绝经,7%报告为手术绝经。自然绝经的平均回忆年龄为48岁,中位回忆年龄为49岁。近三分之一的女性经历过早发/早期绝经(年龄≤45岁)。总体而言,女性报告在过去一个月有任何强度(从轻微到极其困扰)的潮热(30%)、过去12个月有尿失禁(37%)以及有抑郁症状(15%)。绝经症状因绝经时间和类型(自然绝经与手术绝经)而异。特别是,过去一个月有任何强度的困扰性潮热、过去12个月有尿液泄漏以及过去一周有抑郁症状的点患病率,自然绝经的女性分别为28%、37%和14%,手术绝经的女性分别为40%、48%和20%。
南亚裔女性报告的自然绝经回忆年龄早于美国报告的平均年龄52岁。任何强度的潮热、泌尿和情绪障碍负担表明绝经后的经历有所不同。