一只成年罗威纳犬非甾体抗炎药诱发的十二指肠溃疡和穿孔
Nonsteroidal anti-inflammatory drug-induced duodenal ulceration and perforation in a mature rottweiler.
作者信息
Reed Suma
机构信息
Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
出版信息
Can Vet J. 2002 Dec;43(12):971-2.
Abstract
A mature male rottweiler was evaluated for acute collapse and abdominal pain. The history consisted of concurrent administration of meloxicam and aspirin. On exploratory laparotomy, a large perforated ulcer was discovered in the proximal duodenum, with secondary peritonitis. The pathogenesis of NSAID-induced gastrointestinal ulceration and the supposed safety of COX-2 selective agents are discussed.
摘要
对一只成年雄性罗威纳犬进行了急性虚脱和腹痛评估。病史包括同时服用美洛昔康和阿司匹林。在剖腹探查术中，发现十二指肠近端有一个大的穿孔性溃疡，并伴有继发性腹膜炎。本文讨论了非甾体抗炎药引起胃肠道溃疡的发病机制以及COX-2选择性药物的假定安全性。
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