Weiner Matthew A, Read Timothy D, Hanna Philip C
Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan 48104, USA.
J Bacteriol. 2003 Feb;185(4):1462-4. doi: 10.1128/JB.185.4.1462-1464.2003.
We identified a tri-cistronic operon, gerH, in Bacillus anthracis that is important for endospore germination triggered by two distinct germination response pathways termed inosine-His and purine-Ala. Together, the two pathways allow B. anthracis endospores a broader recognition of purines and amino acids that may be important for host-mediated germination.
我们在炭疽芽孢杆菌中鉴定出一个三顺反子操纵子gerH,它对于由两种不同的萌发反应途径(即肌苷-组氨酸途径和嘌呤-丙氨酸途径)触发的芽孢萌发很重要。这两种途径共同使炭疽芽孢杆菌芽孢能够更广泛地识别嘌呤和氨基酸,这对于宿主介导的萌发可能很重要。