Lindqvist P, Henein M, Kazzam E
Department of Clinical Physiology, Sundsvall Hospital, Sundsvall, Sweden.
Eur J Echocardiogr. 2003 Mar;4(1):29-35. doi: 10.1053/euje.2002.0177.
Assessment of right ventricular function is important. However, this is not easy to achieve due to the complex anatomy and geometry of the right ventricle, making the evaluation of its function limited. Therefore, a simple reliable and easy method is needed. This study was performed (1) to evaluate the use of right ventricular outflow tract fractional shortening obtained by M-mode echocardiography as a measure of right ventricular systolic function and (2) to determine the relationship between this parameter and other established measurements of right ventricular function such as long axis excursion.
Ninety-two consecutive patients referred for echocardiographic assessment of left and right ventricular function, age mean+/-SD was 68+/-14 years, were investigated. Twenty healthy controls, age 46+/-12 years were also studied. M-mode echocardiography was used to measure right ventricular outflow tract fractional shortening and right ventricular long axis excursion. Doppler echocardiography was used for the estimation of right ventricular-right atrial pressure drop and pulmonary artery acceleration time. Right ventricular outflow tract fractional shortening (P<0.0001), right ventricular long axis excursion (P<0.0001) and pulmonary acceleration time (P<0.0001) were reduced in patients compared to controls. Right ventricular outflow tract fractional shortening correlated with long axis excursion (r=0.66 P<0.0001), pulmonary artery acceleration time (r=0.80 P<0.0001) and right ventricular-right atrial pressure drop (r=-0.53 P<0.0001). Right ventricular long axis excursion correlated with right ventricular-right atrial pressure drop though to a lesser significance (r=-0.27 P <0.001). Furthermore, right ventricular outflow tract fractional shortening was reduced in patients with pulmonary hypertension compared to patients without, this difference was not observed in the right ventricular systolic long axis excursion.
Right ventricular outflow tract fractional shortening provides a simple and non-invasive measure of right ventricular systolic function. In combination with long axis excursion and Doppler velocities they should provide comprehensive assessment of right ventricular function.
评估右心室功能很重要。然而,由于右心室复杂的解剖结构和几何形态,实现这一点并不容易,这使得对其功能的评估受到限制。因此,需要一种简单可靠且易于操作的方法。本研究旨在:(1)评估通过M型超声心动图获得的右心室流出道缩短分数作为右心室收缩功能指标的应用价值;(2)确定该参数与其他已确立的右心室功能测量指标(如长轴偏移)之间的关系。
对92例因超声心动图评估左、右心室功能而连续就诊的患者进行了研究,患者年龄平均±标准差为68±14岁。还对20名年龄为46±12岁的健康对照者进行了研究。采用M型超声心动图测量右心室流出道缩短分数和右心室长轴偏移。采用多普勒超声心动图估计右心室-右心房压差和肺动脉加速时间。与对照组相比,患者的右心室流出道缩短分数(P<0.0001)、右心室长轴偏移(P<0.0001)和肺动脉加速时间(P<0.0001)均降低。右心室流出道缩短分数与长轴偏移(r=0.66,P<0.0001)、肺动脉加速时间(r=0.80,P<0.0001)和右心室-右心房压差(r=-0.53,P<0.0001)相关。右心室长轴偏移与右心室-右心房压差也相关,但相关性较弱(r=-0.27,P<0.001)。此外,与无肺动脉高压的患者相比,肺动脉高压患者的右心室流出道缩短分数降低,而右心室收缩长轴偏移未观察到这种差异。
右心室流出道缩短分数提供了一种简单且无创的右心室收缩功能测量方法。与长轴偏移和多普勒速度相结合,它们应能提供对右心室功能的全面评估。