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老年人的心血管危险因素:德黑兰血脂与血糖研究

Cardiovascular risk factors in the elderly: the Tehran Lipid and Glucose Study.

作者信息

Azizi Fereidoun, Emami Habib, Salehi Payam, Ghanbarian Arash, Mirmiran Parvin, Mirbolooki Mohammadreza, Azizi Tohid

机构信息

Endocrine Research Center, Shaheed Beheshi University of Medical Sciences, Tehran, Iran.

出版信息

J Cardiovasc Risk. 2003 Feb;10(1):65-73. doi: 10.1097/01.hjr.0000050202.47754.1b.

Abstract

BACKGROUND

Coronary artery disease is becoming more prevalent in developing countries, particularly in urban areas. Because the proportion of elderly individuals in the population is on the rise, this study was conducted to determine the prevalence of cardiovascular risk factors among the Tehran urban elderly population.

DESIGN AND METHODS

Among 15,005 urban individuals of 3 years old and over who had been chosen in a cross-sectional phase of a longitudinal study in Tehran, there were 1,799 people aged 60 years and over. The prevalence and distribution of high blood pressure, cigarette smoking, dyslipoproteinemia, diabetes mellitus and obesity were determined in this population. Dietary intake was assessed in a subsidiary of 54 people by means of two 24 h dietary recalls.

RESULTS

The percentage of women with two or more cardiovascular disease risk factors was significantly greater than in men (74% compared with 53%, P < 0.001). One fourth of men and 55% of women had high serum cholesterol levels (>/=240 mg/dl). The prevalence of diabetes mellitus and impaired glucose tolerance was 24% and 21% in men and 29% and 20% in women, respectively. The prevalence of obesity (body mass index >/=30 kg/m(2)) was 15% for men and 36% for women. Fifty-five per cent of men and 94% of women had high waist-to-hip ratios (>0.95 in men and >0.8 in women). The mean percentage values of energy intake derived from carbohydrate, protein and fat were 60.5 +/- 8.0, 11.5 +/- 2.0 and 27.8 +/- 8.9, respectively.

CONCLUSIONS

The prevalence of cardiovascular risk factors among the Tehran urban elderly population is high. Some efforts should be made to reverse the recent trend towards increasing age-related mortality and morbidity rates of coronary heart disease.

摘要

背景

冠状动脉疾病在发展中国家,尤其是城市地区正变得越来越普遍。由于人口中老年人的比例在上升,因此开展了本研究以确定德黑兰城市老年人群中心血管危险因素的患病率。

设计与方法

在德黑兰一项纵向研究的横断面阶段选取的15005名3岁及以上城市居民中,有1799人年龄在60岁及以上。确定了该人群中高血压、吸烟、血脂异常、糖尿病和肥胖的患病率及分布情况。通过两次24小时饮食回顾对54人的一个子样本进行了饮食摄入量评估。

结果

有两种或更多心血管疾病危险因素的女性比例显著高于男性(分别为74%和53%,P<0.001)。四分之一的男性和55%的女性血清胆固醇水平高(≥240毫克/分升)。男性糖尿病和糖耐量受损的患病率分别为24%和21%,女性分别为29%和20%。肥胖(体重指数≥30千克/平方米)的患病率男性为15%,女性为36%。55%的男性和94%的女性腰臀比高(男性>0.95,女性>0.8)。碳水化合物、蛋白质和脂肪提供的能量摄入平均百分比值分别为60.5±8.0、11.5±2.0和27.8±8.9。

结论

德黑兰城市老年人群中心血管危险因素的患病率很高。应该做出一些努力来扭转近期冠心病年龄相关死亡率和发病率上升的趋势。

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