Mirzaei Masoud, Moayedallaie Setareh, Jabbari Latife, Mohammadi Masoud
Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
University of New South Wales, Sydney, Australia.
J Tehran Heart Cent. 2016 Oct 3;11(4):159-167.
The high prevalence of hypertension and concomitant increase in the risk of its related disease makes it an important health concern all over the world. Hypertension is one of the 5 global leading causes of mortality in the world. Little is known about the current prevalence of hypertension in Iran, however. This systematic review aimed to investigate the current prevalence of hypertension in Iran. A systematic review of hypertension was conducted using international databases, including Medline (PubMed) and Science Direct (Scopus), and Persian scientific databases. The searched keywords were "hypertension", "raised blood pressure", "prevalence", and "Iran". All original articles in English published from 1980 to 2012 were included. After data extraction, heterogeneity between studies and publication bias was assessed and effect size was pooled by the random effect model. Forty-two studies with 402 282 subjects were included. The estimated prevalence of hypertension varied all around Iran (I = 99%). The overall pooled prevalence of hypertension was 22% (95%CI: 20.2 - 23.8). The prevalence of hypertension was 23.6% (95%CI: 21.1 - 26.1) in men and 23.5% (95%CI: 20.2 - 23.8) in women. In urban areas, the prevalence of hypertension was 22.1% (95%CI: 19.4 - 24.7). Ten studies investigated the prevalence of hypertension in rural areas and according to the random effect model, the prevalence of hypertension in rural areas was 18.6% (95%CI: 13.6 - 23.6). Nonsignificant publication bias was found in this review (p value = 0.18). In our meta-regression analysis, only mean age and study quality were associated with significant variability. According to this study, hypertension is one of the most common health problems in Iran. Around one-quarter of the adult population is hypertensive and its prevalence increases by aging. Timely and appropriate public health strategies are essential for the improvement of the screening, treatment, and control of hypertension.
高血压的高患病率及其相关疾病风险的随之增加，使其成为全球重要的健康问题。高血压是全球五大主要死因之一。然而，对于伊朗目前高血压的患病率知之甚少。本系统评价旨在调查伊朗目前高血压的患病率。使用国际数据库（包括Medline（PubMed）和科学Direct（Scopus））以及波斯语科学数据库对高血压进行了系统评价。检索关键词为“高血压”、“血压升高”、“患病率”和“伊朗”。纳入了1980年至2012年发表的所有英文原创文章。数据提取后，评估了研究之间的异质性和发表偏倚，并采用随机效应模型汇总效应量。纳入了42项研究，共402282名受试者。伊朗各地高血压的估计患病率差异很大（I=99%）。高血压的总体合并患病率为22%（95%CI：20.2-23.8）。男性高血压患病率为23.6%（95%CI：21.1-26.1），女性为23.5%（95%CI：20.2-23.8）。在城市地区，高血压患病率为22.1%（95%CI：19.4-24.7）。十项研究调查了农村地区的高血压患病率，根据随机效应模型，农村地区高血压患病率为18.6%（95%CI：13.6-23.6）。本评价发现无显著的发表偏倚（p值=0.18）。在我们的meta回归分析中，只有平均年龄和研究质量与显著变异性相关。根据这项研究，高血压是伊朗最常见的健康问题之一。大约四分之一的成年人口患有高血压，其患病率随年龄增长而增加。及时和适当的公共卫生策略对于改善高血压的筛查、治疗和控制至关重要。
