Yang Jie, Shi Hong, Dong Yong-li, Li Wei-xiang, Zeng Wei-min, Lu Jin, Hao Zhao-qin, Xiao Chun-jie
Human Genetics Center, Yunnan University, Kunming, Yunnan, 650091 PR China.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2003 Feb;20(1):9-11.
To investigate the frequencies distribution of GSTT1 and GSTM1 null genotypes in 24 Yunnan populations.
GSTT1 and GSTM1 genotypes were analyzed by PCR procedure.
The range of frequencies for GSTT1 and GSTM1 null genotypes in the populations were 0.188-0.633 and 0.400-0.745, respectively, and in the districts were 0.286-0.583, 0.433-0.745 respectively. There was significant relationship between GSTT1 frequencies and populations.
The frequencies of GSTT1 and GSTM1 null genotypes in 24 Yunnan populations were different, but they were almost the same in different districts of Yunnan.
研究24个云南人群中谷胱甘肽S-转移酶T1（GSTT1）和谷胱甘肽S-转移酶M1（GSTM1）缺失基因型的频率分布。
采用聚合酶链反应（PCR）方法分析GSTT1和GSTM1基因型。
各人群中GSTT1和GSTM1缺失基因型的频率范围分别为0.188 - 0.633和0.400 - 0.745，各地区的频率范围分别为0.286 - 0.583和0.433 - 0.745。GSTT1频率与人群之间存在显著关系。
24个云南人群中GSTT1和GSTM1缺失基因型的频率不同，但在云南不同地区它们几乎相同。
