Dubey D, Kumar A, Bansal P, Srivastava A, Kapoor R, Mandhani A, Bhandari M
Department of Urology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow-226014, India.
BJU Int. 2003 Feb;91(3):215-8. doi: 10.1046/j.1464-410x.2003.03064.x.
To retrospectively compare the outcome of various techniques of substitution urethroplasty.
Between 1989 and 2000, 109 patients (mean age 39.5 years) underwent substitution urethroplasty for recurrent anterior urethral strictures. Between 1989 and 1995 the procedure was by ventral placement of free grafts (bladder mucosa, buccal mucosa, penile skin) or penile skin flaps. From 1995 onwards the flaps and grafts (buccal mucosa) were applied either ventrally or dorsally. Stricture recurrence and the complications associated with each technique were compared.
Ventral onlay repairs were associated with a higher incidence of complications than dorsal repairs, e.g. postvoid dribbling (39% vs 23%, P = 0.01), ejaculatory dysfunction (20% vs 5%, P = 0.03) and flap/graft pseudo-diverticulum or out-pouching (26% vs 2.6%, P = 0.01). Superficial penile skin necrosis was significantly more common with the use of penile skin flaps than with free grafts. There was no significant difference in stricture recurrence, erectile dysfunction and residual penile deformity among the various techniques.
Dorsal free graft/flap onlay urethroplasty gives better results than ventrally placed free grafts/flaps. Dorsal onlay buccal mucosal urethroplasty is a versatile procedure and associated with fewer complications than other substitution methods.
回顾性比较各种替代尿道成形术的疗效。
1989年至2000年间,109例患者(平均年龄39.5岁)因复发性前尿道狭窄接受了替代尿道成形术。1989年至1995年间,手术方式为腹侧植入游离移植物(膀胱黏膜、颊黏膜、阴茎皮肤)或阴茎皮瓣。从1995年起,皮瓣和移植物(颊黏膜)可植入腹侧或背侧。比较了每种技术的狭窄复发情况及相关并发症。
腹侧覆盖修补术的并发症发生率高于背侧修补术,例如排尿后滴沥(39%对23%,P = 0.01)、射精功能障碍(20%对5%,P = 0.03)以及皮瓣/移植物假性憩室或袋状膨出(26%对2.6%,P = 0.01)。使用阴茎皮瓣时浅表阴茎皮肤坏死比游离移植物更为常见。各种技术在狭窄复发、勃起功能障碍和阴茎残留畸形方面无显著差异。
背侧游离移植物/皮瓣覆盖尿道成形术的效果优于腹侧植入游离移植物/皮瓣。背侧覆盖颊黏膜尿道成形术是一种通用的手术方法,与其他替代方法相比并发症更少。