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[青钱柳多糖降血糖作用的研究]

[Study on reducing blood sugar of polysaccharide from Cyclocarya paliurus (Batal.) Iljinsk].

作者信息

Li Lei, Xie Mingyong, Yi Xing

机构信息

Jiangxi Agricultural University, Nanchang 330045.

出版信息

Zhong Yao Cai. 2002 Jan;25(1):39-41.

PMID:12583243
Abstract

OBJECTIVE

To try to find Cyclocarya paliurus (Batal.) Iljinsk contains the polysaccharide complex with reducing blood-sugar activity or not.

METHOD

The Polysaccharide was extracted by ultrasonic wave. The diabetes model was induced by alloxan to verify the activity of the polysaccharide.

RESULTS

The content of the polgsccharide is 9.6% in Cyclocarya paliurus. The blood-sugar level of the polysaccharide group is lower by 41.3% than that of the diabetes model group. After ig glucose, the blood-sugar level of the pollysaccharide group was obviously lower than that of the diabetes model group.

CONCLUSION

Cyclocarya paliurus (Batal.) Iljinsk is rich in polysaccharide complex, which have obvious reducing blood-sugar activity and can improve the capability of glucose tolerance in diabetes mice.

摘要

目的

探讨青钱柳中是否含有具有降血糖活性的多糖复合物。

方法

采用超声波法提取多糖。用四氧嘧啶诱导糖尿病模型以验证多糖的活性。

结果

青钱柳中多糖含量为9.6%。多糖组血糖水平比糖尿病模型组低41.3%。灌胃葡萄糖后,多糖组血糖水平明显低于糖尿病模型组。

结论

青钱柳富含多糖复合物,具有明显的降血糖活性,能提高糖尿病小鼠的糖耐量。

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[Study on reducing blood sugar of polysaccharide from Cyclocarya paliurus (Batal.) Iljinsk].[青钱柳多糖降血糖作用的研究]
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Cyclocarya paliurus polysaccharides alleviate type 2 diabetic symptoms by modulating gut microbiota and short-chain fatty acids.青钱柳叶多糖通过调节肠道微生物群和短链脂肪酸来缓解 2 型糖尿病症状。
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引用本文的文献

1
Cyclocarya paliurus extract activates insulin signaling via Sirtuin1 in C2C12 myotubes and decreases blood glucose level in mice with impaired insulin secretion.青钱柳提取物通过Sirtuin1激活C2C12肌管中的胰岛素信号,并降低胰岛素分泌受损小鼠的血糖水平。
PLoS One. 2017 Aug 31;12(8):e0183988. doi: 10.1371/journal.pone.0183988. eCollection 2017.