枳椇对糖尿病小鼠血糖及肝糖原的影响
[Effects of Hovenia dulcis Thunb on blood sugar and hepatic glycogen in diabetic mice].
作者信息
Ji Yang, Chen Shan, Zhang Kuirong, Wang Wenjun
机构信息
Drug and Instrument Inspect Institute of PLA, General Rear-Service Department, Beijing 100071.
出版信息
Zhong Yao Cai. 2002 Mar;25(3):190-1.
OBJECTIVE
To observe the effects of Hovenia dulcis Thunb (HDT) on blood sugar and hepatic glycogen in diabetic mice.
METHODS
The diabetes model was established by alloxan and treated with different doses of HDT for 7 days, while the positive control group was treated with glibenclamide. Then the blood sugar and hepatic glycogen were measured.
RESULTS
The blood sugar of mice treated by HDT or glibenclamide significantly lower than diabetes model group. The hepatic glycogen in middle or low dose of HDT and glibenclamide groups was significantly increased.
CONCLUSION
HDT has effect on lowing blood sugar and may become an effective anti-diabetic herb.
目的
观察枳椇子对糖尿病小鼠血糖及肝糖原的影响。
方法
用四氧嘧啶建立糖尿病模型，给予不同剂量的枳椇子治疗7天，阳性对照组给予格列本脲治疗，然后测定血糖和肝糖原。
结果
枳椇子组和格列本脲组小鼠血糖均显著低于糖尿病模型组。枳椇子中、低剂量组和格列本脲组肝糖原均显著增加。
结论
枳椇子具有降血糖作用，可能成为一种有效的抗糖尿病草药。
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