Grundsell H, Håkansson L, Hägerstrand I
Acta Obstet Gynecol Scand. 1976;55(2):155-62. doi: 10.3109/00016347609156805.
The influence of a copper IUD and two "inert" IUDs on the histological picture of the rabbit endometrium during early pseudopregnancy and early pregnancy was studied. The copper IUD markedly inhibited the endometrial maturation during the first five days of both pseudopregnancy and pregnancy. The "inert" IUDs had no such effect. The copper IUD prevented the normal response of the rabbit uterus to 17-beta-estradiol in castrated animals. The observed effects of the copper IUD might seriously interfere with the normal process of implantation.
研究了铜宫内节育器(IUD)和两种“惰性”IUD对家兔假孕早期和妊娠早期子宫内膜组织学表现的影响。铜IUD在假孕和妊娠的头五天均显著抑制子宫内膜成熟。“惰性”IUD则无此作用。铜IUD可阻止阉割动物家兔子宫对17-β-雌二醇的正常反应。观察到的铜IUD的作用可能会严重干扰正常的着床过程。